HORDB

ID: hor001155
Uniprot ID: D9I8P2
Protein name: Neuropeptide AF35
Gene name: AFP-13
Organism: Ascaris suum (Pig roundworm) (Ascaris lumbricoides)
Family: FARP (FMRFamide related peptide) family
Source: Animal
Expression: NA
Disease: NA
Comments: NA
Taxonomy: Ascaris (genus), Ascarididae (family), Ascaridoidea (superfamily), Ascaridomorpha (infraorder), Spirurina (suborder), Rhabditida (order), Chromadorea (class), Nematoda (phylum), Ecdysozoa, Protostomia, Bilateria, Eumetazoa, Metazoa (kingdom), Opisthokonta, Eukaryota (superkingdom), cellular organisms
GO MF: NA
GO BP: GO:0007218 neuropeptide signaling pathway
GO CC: GO:0005576 extracellular region

Sequence: DPQQRIVTDETVLRF
Length: 15(114-128)
Propeptide: MAINSISCLITMLAITVAVSTLESSEIRMLESEFLDGKRGNSYRSFFNPNEYTVVERRDSKLMDPLIRFGKRTNIMGENRLNRNLRAEGLSSPLIRFGKRTPPEEDLLGRFTRDPQQRIVTDETVLRFGRSSAPAAA
Signal peptide: MAINSISCLITMLAITVAVSTLES
Modification: NA
Glycosylation: NA
Mutagenesis: NA

Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)

hor001155_AF2.pdb

hor001155_ESM.pdb

Mass:	206693	Formula:	C79H129N23O26
Absent amino acids:	ACGHKMNSWY	Common amino acids:	DQRTV
pI:	4.37	Basic residues:	2
Polar residues:	2	Hydrophobic residues:	5
Hydrophobicity:	-66.67	Boman Index:	-4941
Half-Life / Aliphatic Index:	1.1 hour	Aliphatic Index:	90.67
Instability Index:	3653.33	Extinction Coefficient cystines:	0
Absorbance 280nm:	0

PubMed ID: 20806053
Title: Mapping Neuropeptide Expression by Mass Spectrometry in Single Dissected Identified Neurons From the Dorsal Ganglion of the Nematode Ascaris Suum